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UNE POLITIQUE D’INNOVATION ORIGINALE

Les Mérieux « Research Grants »

Ces contrats de recherche ont pour objectif de susciter et identifier des projets innovants. Ils financent des investigateurs (juniors ou seniors, médecins ou scientifiques) pour des projets réalisés dans des laboratoires privés ou publics, dans le domaine des maladies infectieuses, des cancers et maladies cardiovasculaires, de la sécurité alimentaire, de la nutrition et de l’eau.

Au terme d’une sélection rigoureuse, les investigateurs retenus, reçoivent un financement sur 2 ans ( jusqu’à 300 000 € ), l’Institut Mérieux se réservant la possibilité de nouer des partenariats stratégiques en cas de succès.

Deux types de contrats coexistent :
  • les « Advanced Research Grants » pour les projets les plus innovants présentant des enjeux stratégiques importants
  • les « Starting Research Grants » pour des projets intéressants mais devant clairement montrer leur faisabilité.
Merieux Alliance

Projets sélectionnés

Mérieux Research Grants 2011

Sylvie ALONSOSingapore
partenariat avec l’Université de Sharjah

  • Latent tuberculosis: investigating the mechanisms involved in Mycobacterium tuberculosis survival within lysosomes of macrophages. Starting grant

Frederic BIENVENUInserm – Montpellier - France
partenariat avec l’Université de Sharjah

  • Transcription-Nuclear Export Coupling as a New Cancer Diagnosis-Prognosis and Therapeutic Target Starting grant

Hua CUIUniversity of Science and Technology of China – Hefei - China

  • Luminescence Functionalized Nanoprobes for chemiluminescence bioassays Starting grant

Eleftherios DIAMANTISMount Sinai Hospital, Toronto - Canada

  • Towards non-invasive diagnosis of urogenital diseases by a novel multiparametric biomarker panel in seminal plasma Advanced grant

Marc-Emmanuel DUMAS – Charles COOMBESImperial College - London

  • Signalling Mechanisms of Metabolic Syndrome by The Gut Microbiota Metabolome
  • Predictive modelling of systemic adjuvant therapy outcomes in breast cancer patients Advanced grant

Hussam HAICKTechnion – Haifa - Israel

  • Screening, Diagnosis and Monitoring of Prostate Cancer via Exhaled Breath Using an Array of Nanosensors Advanced grant

Na LIPeking University – Beijing - China

  • Foodborne Pathogen Detection using Saccharide Capped Gold Nanoparticles Starting grant

Jianfeng LIUHuazhong University of Science and Technology – Wuhan - China

  • The theranostics biomarker identification in the GABAB receptor/Akt complex for human cancer metastasis treatment Advanced grant

Jeremy NICHOLSON - Elaine HOLMESImperial College - London

  • Quantitative microbial co-metabolite biomarker analysis in acute medicine and public health”. Advanced grant

Sanjay PHOGATIavi - New York - US

  • Novel High-Throughput Screening Selection Strategy to identify HIV Advanced grant

Jacques SAMARUTENS – Lyon - France
partenariat avec l’Université de Sharjah

  • Signaling pathways of nuclear receptors in human prostate and colon tumors : toward identification of new pathology biomarkers Starting grant

Hui-Chuan SUNZhongshan Hospital, - Shanghai - China

  • Study of gene expression profile of tumor endothelial cells in hepatocellular carcinoma Starting grant

Jia-Chang YUEInstitute of Biophysics, CAS – Beijing - China

  • Protein motor F0F1-ATPase constructing vital virus biosensor Starting grant

Mérieux Research Grants 2010

Emile BEAULIEUnserm – Collège de France Paris

  • Novel approach of the prevention/treatment of naturopathies with dementia, including Alzheimer’s diseases - Emergency of FKBP52 immunophilin function an Tay pathophysiology

Francis CHISARIScripps – La Jolla

  • Induction of the interferon response by the Hepatitis C Virus

Jeffrey GORDONWashington University - Saint Louis - USA

  • A metagenomic study using humanized gnotobiotic mice to characterize the effects of malnutrition and the gut microbiota on vaccine response

Daniel KALMANEmory University - Atlanta

  • Development of novel therapeutics for treating MTB infection

Anne O’GARRANational Institute for Medical Research

  • Transcriptional signatures in human tuberculosis 

Michael ROUKESKavli Nanoscience Institute

  • Mass spectrometry based on NEMS arrays (NEMS-MS)

Philippe SANSONETTIInstitut Pasteur Paris

  • Deciphering the regulation of innate antimicrobial peptides to develop innovative anti-infectious drugs

Hong-Bin SHUUniversity Wuhan

  • Molecular mechanisms of cellular antiviral response

Luc TEYTONScripps – La Jolla

  • Development of a new immunomodulators using High Troughtup sreening

Zhouping WANGJiangnan University - Wuxi

  • Aptamer recognition and nanostructure sensing based on ultrasensitive bioanalysis for food nutrition and food safety

Bob WEINBERGWhitehead Institute for Biomedical Research - Cambridge

  • Factors Regulating the Stem Cell State of Normal and Neoplastic Cells

Chen Yu ZHANGSchool of life Sciences Nanjing University

  • Milk MicroRNA expression profile as a novel biomarker for raw milk quality detection

Mérieux Research Grants 2009

Francis ALBARDEENS (Ecole Normale Supérieure) in Lyon - France

  • the natural isotopic variability of metals associated with some cancer pathologies

Xiang DUFudan University Cancer Hospital in Shanghai - China

  • Seeking the Novel Biomarkers in Colorectal microRNAome

Lee-Ann JAYKUSFood Science Department North Carolina State University in Raleigh - USA

  • Development and application of novel approaches for human enteric virus concentration and purification from complex sample in support of rapid molecular-based detection

Jan KARLSEDERSalk Institute for Biological Studies, in La Jolla, California - USA

  • C. elegans as a model for telmomere Length Regulation in cancer

Pierre MIOSSECHospices Civils de Lyon - France

  • IL-17 and Th17 cells in rheumatoid arthritis

Germain PUZOCNRS (Centre National de la Recherche Scientifique) et University Paul Sabatier in Toulouse - France

  • Sulfoglycolipid antigens as subunit candidate TB vaccine

Philippe ROINGEARDUniversity François Rabelais in Tours - France

  • New fusion proteins and their application for preparation of hepatitis C vaccines

Ajit VARKIUniversity of California, San Diego - USA

  • Roles of a Non-human Sialic Acid in Cancer, Cardiovascular Diseases and Food and Drug Safety

Inder VERMASalk Institute for Biological Studies, in La Jolla, California - USA

  • Glioblastoma : The rôle of NF kB and its potential as therapeutictarget

Zhiwei WUNanjing University in Nanjing - China

  • Design of an innate immune agent as an HIV-1 entry inhibitor

Rong ZHOUGuangzhou Institute of Respiratory Diseases in Guangzhou - China

  • Study on trivalent vaccine against human adenovirus and a “virus display” platform for vaccine development